Upregulation of Twist-1 by NF-κB Blocks Cytotoxicity Induced by Chemotherapeutic Drugs
نویسندگان
چکیده
منابع مشابه
Ferritin Heavy Chain Upregulation by NF-κB Inhibits TNFα-Induced Apoptosis by Suppressing Reactive Oxygen Species
al., 2002). Cytotoxicity caused by ROS is mediated in part by the JNK pathway (Matsuzawa et al., 2002). Acti-During inflammation, NF-B transcription factors an-vation of this pathway by TNF␣ promotes death by in-tagonize apoptosis induced by tumor necrosis factor ducing cleavage of the Bcl-2 family BH3-only protein, (TNF)␣. This antiapoptotic activity of NF-B involves Bid, into jBid, which ta...
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ژورنال
عنوان ژورنال: Molecular and Cellular Biology
سال: 2007
ISSN: 0270-7306,1098-5549
DOI: 10.1128/mcb.01219-06